The Binding of Isaac: Repentance

Lazarus

Common52.9%

Have 4 or more soul hearts at one time

The Womb

Common50.3%

Kill Mom.

Azazel

Common47.0%

Make 3 deals with the devil in one run.

Cain

Common46.4%

Hold 55 or more pennies at one time.

Magdalene

Common46.0%

Have 7 or more max red hearts at one time.

Little Baggy

Common45.3%

Collect 2 of either Roid Rage, The Virus, Growth Hormones, Experimental Treatment, or Speed Ball.

Eve

Common43.4%

Beat 2 levels in a row without picking up any hearts.

The Book of Sin

Common42.8%

Kill all 7 sins.

Eden

Common42.6%

Beat the Womb for the first time.

Boss Rush

Uncommon38.6%

Beat the Boss Rush.

Samson

Uncommon37.7%

Beat 2 levels in a row without taking damage.

Transcendence

Uncommon37.3%

Kill Mom's Heart 3 times.

Basement Boy

Uncommon36.4%

Beat the Basement/Cellar without taking damage.

Something from the Future

Uncommon34.9%

Beat the Basement 40 times.

Everything Is Terrible

Uncommon34.6%

Kill Mom's Heart 5 times.

Judas

Uncommon33.5%

Kill Satan

Something Cute

Uncommon31.7%

Beat the Caves 30 times.

Lilith

Uncommon31.7%

Beat Greed Mode with Azazel

A Quarter

Uncommon31.6%

Kill Mom's Heart 8 times.

Something Sticky

Uncommon31.4%

Beat the Depths 20 times.

A Fetus in a Jar

Uncommon30.9%

Kill Mom's Heart 9 times.

Blue Baby

Uncommon30.4%

Kill Mom's Heart 10 times.

It Lives

Uncommon29.8%

Kill Mom's Heart 11 times.

The Halo

Uncommon29.4%

Kill Mom using the Bible.

Dark Room

Uncommon27.9%

Beat the Dark Room.

Daemon's Tail

Uncommon27.2%

Kill Satan with Azazel.

The Chest

Uncommon27.0%

Beat the Chest.

Mom's Knife

Uncommon26.0%

Kill Satan with Isaac.

The Satanic Bible

Uncommon25.1%

Kill Isaac with Azazel.

New Area

Uncommon25.1%

Unlocked a new area

The Gate is Open!

Uncommon25.1%

Kill The Lamb

The Polaroid

Uncommon24.6%

Beat Cathedral 5 times.

Isaac's Tears

Uncommon24.6%

Kill Isaac with Isaac.

The Negative

Uncommon24.1%

Beat Sheol 5 times.

Spelunker Boy

Uncommon24.0%

Beat the Caves/Catacombs without taking damage.

Mama's Boy

Uncommon22.4%

Beat the Womb/Utero without taking damage.

Bethany

Uncommon22.3%

Beat Hard mode as Lazarus without losing a life

Golden God

Uncommon21.8%

You are the best!

A Secret Exit

Uncommon21.8%

Complete ??? 3 times.

Delirious

Uncommon21.6%

Beat Delirium

Apollyon

Uncommon21.3%

Kill Mega Satan

Lost Poster

Uncommon20.4%

Beat the Dark Room with Isaac.

The Bomb Bag

Uncommon19.5%

Kill Satan with Cain.

The Coin Bag

Uncommon19.4%

Kill Isaac with Cain.

Dark Boy

Uncommon19.3%

Beat the Depths/Necropolis without taking damage.

A Blank Card

Uncommon17.7%

Kill Isaac with Eden.

Dead Boy

Uncommon17.2%

Beat the Chest or Dark Room without taking damage.

Jacob & Esau

Uncommon17.1%

You are just like your father...

The Guillotine

Uncommon16.7%

Kill Isaac with Judas.

The Book of Secrets

Uncommon16.6%

Kill Satan with Eden.

Red Key

Uncommon16.5%

The other side is calling...

Judas' Tongue

Uncommon16.1%

Kill Satan with Judas.

The Relic

Uncommon16.1%

Kill Isaac with Maggy.

Guardian Angel

Uncommon15.7%

Kill Satan with Maggy.

Greedier!

Uncommon14.9%

Donate 500 coins to the Greed Machine

Lazarus' Rags

Uncommon14.8%

Kill Isaac with Lazarus.

The Lost

Uncommon14.6%

Finish the game's final secret.

Broken Ankh

Uncommon14.4%

Kill Satan with Lazarus.

Bloody Lust

Uncommon14.2%

Kill Isaac with Samson.

Blood Rights

Uncommon13.6%

Kill Satan with Samson.

The Forgotten

Uncommon13.0%

Uncover some lost remains..

Eve's Bird Foot

Uncommon12.7%

Kill Isaac with Eve.

The Razor

Uncommon12.1%

Kill Satan with Eve.

1001%

Uncommon11.7%

Collect all items and unlock all secrets

Forget Me Now

Uncommon11.6%

Kill Satan with ???.

Keeper

Uncommon11.4%

Donate 1000 coins in Greed Mode

Isaac's Heart

Rare9.8%

Kill Isaac with The Lost.

Cambion Conception

Rare9.7%

Kill ??? with Lilith

The Mind

Rare9.6%

Kill Satan with The Lost.

Succubus

Rare8.8%

Kill The Lamb with Lilith

Deep Pockets

Rare7.2%

Kill ??? with Keeper

Karma

Rare6.4%

Kill The Lamb with Keeper

1000000%

Rare5.1%

Just Stop!

Mega Mush

Very rare1.9%

Beat everything in Hard Mode as every character.

Platinum God

Very rare1.5%

Collect all items and unlock all secrets and endings.

Real Platinum God

Very rare1.4%

100% the game!

Challenges

Very rare1.0%

Beat all 20 Challenges.

Death Certificate

Ultra rare0.9%

...

Dead God

Ultra rare0.6%

RIP