Sapphire

Beat the Spire with the Defect. Orbs are the name of the game - Frost for defence, Lightning for chip damage, and Focus (Defragment/Biased Cognition) to buff them all at once. The easy win is a Frost/Focus tank deck (Glacier, Chill, Defragment) that just out-blocks everything, or a Lightning swarm with Electrodynamics. Once your orbs snowball the Defect is arguably the strongest class in the game.