Who Needs Relics?

Win while holding just one relic. You keep your starting relic (that's your one), so the run is about not picking up any more. The big catch: elite fights auto-grant a relic you can't decline, so you must avoid every elite - route around them on the map. Skip relic rewards, don't open treasure chests (take the skip), dodge relic events, skip the boss relic reward, and at shops only ever buy cards/potions/removal - never relics. It's very doable on a lower Ascension; just be disciplined about leaving relics on the floor. Combine with Minimalist and Purity for a triple-dip minimalist run.