No missable achievements (plus 53 unknown)
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Upgraded a weapon at a Power to the People Station.
Bought one Plasmid Slot or Tonic Slot at a Gatherer's Garden.
Researched a Splicer with the Research Camera.
Installed the third upgrade to a weapon.
Defeated 3 Big Daddies without dying during a fight.
Hacked one of each kind of machine.
Fully upgraded one Plasmid to the Level 3 version.
Dealt with every Little Sister.
Fully upgraded to the maximum number of Plasmid Slots.
Maxed out one Research Track.
Got through a Gather with no damage and no one getting to the Little Sister.
Kill a Lancer Big Daddy
Finished the game without using Vita-Chambers.
Resolved all the Little Sisters in Minerva's Den
Found or purchased all 11 basic Plasmid types.
Spent 2000 Dollars at Vending Machines.
Finished the game on the hardest difficulty level.
Destroyed all 10 Vacuum Bots in Minerva's Den
Collected 100% of the ADAM in a single Protector Trial.
Earned 6 stars in the Protector Trials
Killed 30 enemies using only Traps.
Earned 18 stars in the Protector Trials
Collected 50% of the ADAM available in all Protector Trials.
Earned 36 stars in the Protector Trials
Earned an A rank in all Protector Trials
Found every Power to the People weapon upgrades in the game.
Find 100 Audio Diaries.
Hacked 30 machines at a distance with the Hack Tool.
Completed all research on every subject in Rapture.
Gather 600 ADAM with Little Sisters.