No missable achievements (plus 44 unknown)
Sign in with Steam or Xbox to track your progress, and:
Defeat Big Bandit.
Defeat Big Dog.
Defeat Lil Hunter.
Unlock a Golden Weapon as any character.
Reach 2-? as Eyes.
Reach the Nuclear Throne.
Loop the game.
Reach 4-? as Crystal.
Unlock a Crown as any character.
Reach Level Ultra as any character.
Reach 7-3 on a Daily.
Unlock a Golden Weapon for every character.
Reach the Nuclear Throne in under 10 minutes as Plant.
Loop as every character.
Reach the Nuclear Throne with Melting without choosing Rhino Skin or Strong Spirit.
Unlock all Crowns as one character.
Get 100% of the unlocks.