No missable achievements (plus 12 unknown)
Sign in with Steam or Xbox to track your progress, and:
Get the syrup in the pharmacy before going to Twinsen's house.
Talk to the Star Wars fanboy.
Get the magic saber.
Finish the game.
Unlock all the clover boxes.
Unlock the 4 videos in which Twinsen gets a slap.
Get into the meca-pinguin room.
Have at least 500 Kashes in your wallet.
Find the secret passage in the museum.
Fire the canon in the museum.
Unlock the second video of the ferry trip.
Finish the game in less than 4h.