No missable achievements (plus 16 unknown)
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Defeat the wurm boss.
Shoot at least one bullet that does 3x damage.
Take 15 damage in a single successful run.
Beat the green final boss.
Beat the yellow final boss.
Destroy 5 Angel Globs in a single run.
Beat the blue final boss.
Get a total of 14 hearts in a single run.
Complete a run in under 20 minutes.
Get the banana, orange, and almond powerups all in one run.
Collect each type of powerup at least once.
Complete a run after choosing the plum powerup before entering the Owl.
Get the egg, spicy ball, and cherry powerups all in one run.
Complete a run after choosing the poison berries before entering the Owl.
Complete a run without taking any damage.