No missable achievements (plus 44 unknown)
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Defeat a zombie.
Die for the first time.
Defeat a Crimson Head.
Burn up a zombie.
Defeat mother Neptune.
Defeat a Hunter.
Save Richard with a serum.
Defeat Black Tiger.
Survive your first encounter with Yawn.
Finish the game on Very Easy difficulty or higher.
Defeat a Crimson Head prototype1 using Jill.
Save Jill using Barry.
Obtain the Helmet Key using Jill.
Defeat Yawn using Jill.
Break into the laboratory using Jill.
Obtain the Stone & Metal Object using Chris.
Finish the game using Jill.
Save Barry from Lisa Trevor.
Save Chris from confinement using Jill.
Defeat Plant 42 using Chris.
Finish the game on Easy difficulty or higher.
Obtain the "Last Book Vol. 2" using Chris.
Defeat Lisa Trevor using Chris.
Finish the game saving Chris and Barry using Jill.
Finish the game using Chris.
Save Jill from confinement using Chris.
Save Chris using Rebecca.
Save Rebecca from a Hunter.
Burn up two zombies at the same time with the lighter.
Finish the game saving Rebecca and Jill using Chris.
Finish the game with Jill and Chris.
Finish the game on Normal difficulty or higher.
Finish the game in five hours.
Finish the game without saving anyone using Jill.
Finish the game on Hard difficulty.
Finish the game in three hours.
Finish the game without saving anyone using Chris.
Visit all places on all maps.
Finish the game without saving.
Obtain all costumes.
Obtain all weapons (must load grenade launcher with all shell types).
Finish the game using only your knife (no lighter, Defensive Items, and stomping zombie heads).
Finish the game in Real Survival mode.
Finish the game in Invisible Enemy mode.