No missable achievements (plus 68 unknown)
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Found your way back into the ruins of Rapture.
Used the Hack Tool to hack an object at a distance.
Defended yourself against Lamb's assault in the train station.
Upgrade any weapon at a Power to the People Station.
Adopted a new Little Sister for the first time.
Joined forces with Sinclair in Ryan Amusements.
Research a Splicer with the Research Camera.
Successfully hack at least one of every type of machine
Buy one Plasmid or Tonic Slot at a Gatherer's Garden.
Defended yourself against the Big Sister without dying.
Confronted Lamb’s lieutenant in Pauper’s Drop.
Spend 2000 dollars at Vending Machines.
Install the third and final upgrade to any of your weapons.
Defeated the Preacher.
Defeat 3 Big Daddies without dying during the fight.
Uncovered the secret of Dionysus Park.
Fully upgrade one of your Plasmids to the level 3 version at a Gatherer's Garden.
Gained access to Lamb’s stronghold.
Reunited with your original Little Sister.
Headed to the surface on the side of Sinclair's escape pod.
Escaped Rapture.
Gather 600 ADAM with Little Sisters.
Either Harvest or Save every Little Sister in the game.
Killed 50 enemies using only hacked Security.
Hack 30 machines at a distance with the Hack Tool.
Fully upgrade to the maximum number of Plasmid Slots.
Killed an enemy with its own projectile.
Kill 30 enemies using only Traps.
Max out one Research Track.
Get through a Gather with no damage and no one getting to the Little Sister.
Saved every Little Sister and spared Grace, Stanley and Gil.
Find 100 audio diaries.
Kill a Lancer Big Daddy
Reached Rapture Central Computing Operations
Find all 14 Power to the People weapon upgrades in the game.
Reached Computer Core Access
Wrested control of the Thinker from Reed Wahl
Escaped Minerva's Den
Finish the game without using Vita-Chambers.
Resolve all the Little Sisters in Minerva's Den
Find or purchase all 11 basic Plasmid types.
Paid your respects to the founder of Rapture.
Finish the game on the hardest difficulty level.
Max out research on all 9 research subjects.
Destroy all 10 Vacuum Bots in Minerva's Den
Earn 6 stars in the Protector Trials.
Collect 100% of the ADAM in a single Protector Trial
Earn 18 stars in the Protector Trials.
Get 9999 points in a single game of spitfire
Collect 50% of the ADAM available in all Protector Trials
Earn 36 stars in the Protector Trials.
Earn an A rank in all Protector Trials
Completed all bonus Protector Trials.